Reprogramming following somatic cell nuclear transfer in primates is dependent upon nuclear remodeling
نویسندگان
چکیده
منابع مشابه
Reprogramming following somatic cell nuclear transfer in primates is dependent upon nuclear remodeling.
BACKGROUND Somatic cell nuclear transfer (SCNT) requires cytoplast-mediated reprogramming of the donor nucleus. Cytoplast factors such as maturation promoting factor are implicated based on their involvement in nuclear envelope breakdown (NEBD) and premature chromosome condensation (PCC). Given prior difficulties in SCNT in primates using conventional protocols, we hypothesized that the ability...
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ژورنال
عنوان ژورنال: Human Reproduction
سال: 2007
ISSN: 1460-2350,0268-1161
DOI: 10.1093/humrep/dem136